Pulmonary artery hypertension: pertinent vasomotorial cytokines.

Pulmonary artery hypertension: pertinent vasomotorial cytokines.
Eur Cytokine Netw. 2017 Mar 01;28(1):1-7
Authors: Yuan SM
Abstract
Pulmonary artery hypertension is a syndrome that shows similar clinical and pathophysiological features characterized by elevated pulmonary arterial pressure and resistance. There have been a series of hypotheses trying to describe the development of pulmonary artery hypertension; however, none of them perfectly explains its pathogenesis. To highlight the pathogenesis, novel vasomotorial cytokines including hypoxia-inducible factor-1α, endothelin-1, urotensin II, Krüppel-like factor 4, calcitonin gene-related peptide, angiopoietins, and serotonin closely related to pulmonary artery hypertension are discussed. The development of the new agents relating to these cytokines may improve the relevant treatment strategies.
PMID: 28840840 [PubMed - in process]

Source: European Cytokine Network - August 27, 2017 Category: Molecular Biology Tags: Eur Cytokine Netw Source Type: research