Does Lipitor Help Rheumatoid Arthritis?

Title: Does Lipitor Help Rheumatoid Arthritis?Category: Doctor's&Expert's views on SymptomsCreated: 8/15/2017 12:00:00 AMLast Editorial Review: 8/15/2017 12:00:00 AM
Source: MedicineNet Arthritis General - Category: Rheumatology Source Type: news

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We examined the incidence rate and risk factors of osteoporotic vertebral fracture in RA patients with new-onset CVD (RA-CVD) and evaluated the effects of medications on such fracture risk.MethodsA retrospective study was conducted using a nationwide database from 2000 to 2010: 1267 RA-CVD and 1267 non-CVD patients were enrolled from 30,507 patients with newly diagnosed RA. The main outcome was the development of osteoporotic vertebral fracture. After being adjusted for age, gender, and comorbidities, the Cox proportional hazard model was used to identify independent factors contributing to osteoporotic vertebral fracture....
Source: Osteoporosis International - Category: Orthopaedics Source Type: research
Joseph D. Romano1,2,3,4 and Nicholas P. Tatonetti1,2,3,4* 1Department of Biomedical Informatics, Columbia University, New York, NY, United States 2Department of Systems Biology, Columbia University, New York, NY, United States 3Department of Medicine, Columbia University, New York, NY, United States 4Data Science Institute, Columbia University, New York, NY, United States The discovery of new pharmaceutical drugs is one of the preeminent tasks—scientifically, economically, and socially—in biomedical research. Advances in informatics and computational biology have increased productivity at many stag...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
FRIDAY, April 19, 2019 -- Daily atorvastatin is safe for the primary prevention of cardiovascular events (CVE) in patients with rheumatoid arthritis, conferring a similar degree of risk reduction in these patients as in other populations, according...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Giuseppe Ristagno1*, Francesca Fumagalli1, Barbara Bottazzi2, Alberto Mantovani2,3,4, Davide Olivari1, Deborah Novelli1 and Roberto Latini1 1Department of Cardiovascular Research, Mario Negri Institute for Pharmacological Research IRCCS, Milan, Italy 2Humanitas Clinical and Research Center-IRCCS, Milan, Italy 3Humanitas University, Milan, Italy 4The William Harvey Research Institute, Queen Mary University of London, London, United Kingdom The long pentraxin PTX3 is a member of the pentraxin family produced locally by stromal and myeloid cells in response to proinflammatory signals and microbial moieties. The p...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
ConclusionIn this post ‐hoc analysis, after 24 weeks of tofacitinib, increased HDL‐c, but not increases in LDL‐c or TC, appeared to be associated with lower future MACE risk. Further data are needed to test the cardiovascular safety of tofacitinib.This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Tags: Full Length Source Type: research
Patients with rheumatoid arthritis are likely to experience the same level of cardiovascular benefits as other individuals Related items fromOnMedica Lifestyle intervention in type 2 diabetes can have long-term effect Heart disease and stroke deaths plummet in Scotland Brexit could result in thousands of extra CVD deaths CHD and stroke risk seriously elevated with just one daily cigarette Obesity associated with worse mortality and higher CVD risk
Source: OnMedica Latest News - Category: UK Health Source Type: news
Conclusions In recent years, there have been many advances in the understanding of the molecular basis for vascular involvement in APS, but many areas need to be further investigated, in particular the association between altered genetic/epigenetic profiles, autoantibodies and clinical manifestations, and the effectiveness of new therapeutic strategies. It would be interesting to apply next generation sequencing technologies like RNA-Seq along with GWAS to screen both, the gene profile and the whole transcriptome of large cohorts of primary APS patients, in order to reveal the mutations/polymorphisms, post-transcriptiona...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Influence of Habitual Physical Behavior – Sleeping, Sedentarism, Physical Activity – On Bone Health in Community-Dwelling Older People Gladys Onambele-Pearson1*, Jorgen Wullems1,2, Conor Doody1, Declan Ryan1,3, Christopher Morse1 and Hans Degens4,5,6 1Department of Exercise and Sport Science, Manchester Metropolitan University, Manchester, United Kingdom 2Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium 3Faculty of Health and Society, University of Northampton, Northampton, United Kingdom 4School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom 5In...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Statins are safe and likely effective for preventing cardiovascular events among patients with rheumatoid arthritis, but not every patient with RA needs the drug, new data suggest.Medscape Medical News
Source: Medscape Cardiology Headlines - Category: Cardiology Tags: Rheumatology News Source Type: news
(Wiley) Results from a large clinical trial indicate that patients with rheumatoid arthritis are likely to experience the same level of cardiovascular benefits from statins as other individuals, without additional risks. The findings appear in Arthritis&Rheumatology, an official journal of the American College of Rheumatology.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
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