Norovirus Loads in Stool Specimens of Cancer Patients with Norovirus Gastroenteritis

In this study, a validated real-time quantitative PCR (qPCR) assay was used to determine viral loads NoV genogroup I and II (GI and GII) in NoV positive stool specimens of cancer patients. A total of 234 specimens from 152 patients were positive for NoV, including 201 of GII and 33 of GI. Geometric mean of logarithmic copies (GMLC) per gram of stool (w/w) of NoV-GII were 9.03 ±1.71 (mean ± standard deviation), which was significantly higher than that of NoV-GI (7.87±1.49) (OR=3.22; 95% CI = 1.33 to 7.76, P =0.009).
Source: Journal of Molecular Diagnostics - Category: Pathology Authors: Tags: Regular Article Source Type: research