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Racial gap narrows in heart attack deaths

The data from the University of Iowa show black patients now have a 21.4 percent chance of surviving, compared to whites' 23.2 percent. That is up from 11 percent and 16 percent in 2000.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Authors: Schäfer A, Bauersachs J Abstract Single antiplatelet therapy (SAPT) using predominantly acetylsalicylic acid (ASA) is the baseline anti-thrombotic therapy in primary as well as secondary prevention of atherosclerotic disease. Dual antiplatelet therapy (DAPT) is the cornerstone of maintenance medication following elective percutaneous coronary interventions or acute coronary syndromes (ST elevation myocardial infarction, non-ST elevation myocardial infarction and unstable angina pectoris). In the past the duration of DAPT in particular has been frequently discussed. Current recommendations, such as the...
Source: Herz - Category: Cardiology Tags: Herz Source Type: research
Authors: Schlitt A, Guha M, Noutsias M, Klein HH, Klein HU Abstract Assessment of a permanent risk of life-threatening ventricular arrhythmia in patients with severely reduced left ventricular ejection fraction (LVEF
Source: Herz - Category: Cardiology Tags: Herz Source Type: research
Obesity and overweight can lead to a heart attack, stroke, or diabetes. Yet, there are other ways to determine someone ’s chances of developing a cardiometabolic health condition. According to a recentstudy presented at the Radiological Society of North America annual meeting, the way fat is distributed throughout the body can indicate someone ’s cardiometabolic risk. Study lead Miriam A. Bredella, MD, a radiologist at Massachusetts General Hospital and associate professor at Harvard Medical School, and her colleagues evaluated 200 overweight and obese people who were the mean age of 37 and had similar BMI. The...
Source: radRounds - Category: Radiology Authors: Source Type: blogs
Randomized controlled trials (RCTs) have shown fractional flow reserve-guided (FFR) multivessel stenting to be superior to infarct-related artery (IRA) only stenting in patients with ST-elevation myocardial infarction (STEMI) and multivessel disease. This effect was mainly driven by a reduction in overall repeat revascularization. However, the ability to assess the effect of this strategy on urgent revascularization or reinfarction was underpowered in individual trials.
Source: International Journal of Cardiology - Category: Cardiology Authors: Source Type: research
Authors: Rashid HN, Gooley RP, Nerlekar N, Ihdayhid AR, McCormick LM, Nasis A, Cameron JD, Brown AJ Abstract AIMS: Leaflet thrombosis (LT) has become increasingly recognised following transcatheter and surgical aortic ABV replacement and can be reliably identified by MDCT. However, it is ongoing debate whether MDCT-defined LT is associated with adverse cerebrovascular outcomes. We performed a systematic review and meta-analysis to assess the incidence and clinical outcomes associated with multidetector computed tomography (MDCT)-defined leaflet thrombosis following aortic bioprosthetic valve (ABV) replacement. ...
Source: EuroIntervention - Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research
Conclusions: In the ABSORB China trial, BVS and CoCr-EES had similar results up to three-year follow-up, the time at which the scaffold has completely resorbed. BVS outcomes may be further optimised by appropriate lesion selection and implantation technique. PMID: 29235306 [PubMed - as supplied by publisher]
Source: EuroIntervention - Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research
Authors: Figueredo VM Abstract Preview The purpose of risk stratification in survivors of acute myocardial infarction is to identify those most likely to have subsequent cardiac events and, if possible, to improve their prognosis with medical therapy, revascularization, or both. Dr Figueredo reviews methods of assessing risk and discusses the merits and limitations of each. PMID: 29231112 [PubMed]
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
A key feature of acute myocardial infarction (AMI) is an alteration in cardiac architecture. Signaling events that result in the inhibition of glycogen synthase kinase-3 (GSK-3)β represent an adaptive response that might limit the extent of adverse remodeling in the aftermath of AMI. Here, we report that an allosteric inhibitor of GSK-3β, 4-benzyl-2-(naphthalene-1-yl)-1,2,4-thiadiazolidine-3,5-dione (NP12), lessens the magnitude of adverse myocardial remodeling and promotes angiogenesis. Male and female mice 8–10 weeks old were grouped (six animals in each group) into sham surgery (sham group), left anterio...
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Gene Regulation Source Type: research
Conclusions: The results suggested that the expression of miR-126-enhanced ADSC-derived exosomes prevented myocardial damage by protecting myocardial cells from apoptosis, inflammation, fibrosis, and increased angiogenesis.Cell Physiol Biochem 2017;44:2105 –2116
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research
3 out of 5 stars Fewer adverse effects with a modified two-bag acetylcysteine protocol in paracetamol overdose. McNulty R et al. Clin Toxicol 2017 Dec 8 [Epub ahead of print] Abstract Current recommendations for dosing intravenous N-acetylcysteine (Acetadote) for treating acute acetaminophen (paracetamol) poisoning involves a somewhat complex three-bag protocol, using 3 direct concentrations of the antidote given over a 21-hour period. Unfortunately, this protocol results in a high incidence of (usually mild) adverse events, including cutaneous effects, nausea and vomiting, and anaphylactoid reactions. Severe rea...
Source: The Poison Review - Category: Toxicology Authors: Tags: Medical Acetadote acetaminophen antidote N-acetylcysteine paracetamol three-bag protocol toxicity two-bag protocol Source Type: news
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