First Head-to-Head of Chemo for Prostate Cancer First Head-to-Head of Chemo for Prostate Cancer

The first head-to-head comparison of two chemotherapies for prostate cancer finds similar survival gains but different toxicity profiles.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

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CONCLUSION: This is the first case to our knowledge describing both such lesions in one patient and the first case describing the use of 2-(3-{1-carboxy-5-[(6-[18F]fluoro-pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pentanedioic acid (18F-DCFPyL)-PSMA PET/CT to detect IPAS. Furthermore we highlight the value of nuclear medicine diagnostic work up in complex cases. PMID: 30006647 [PubMed - as supplied by publisher]
Source: Hellenic Journal of Nuclear Medicine - Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research
PROSTATE cancer happens when cells in the prostate, part of the male reproductive system, begin to divide uncontrollably. Early warning signs and symptoms of the cancer include difficulty urinating and needing to go to the toilet more regularly. But, how do doctors check for prostate cancer?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
PROSTATE cancer happens when cells in the prostate, part of the male reproductive system, begin to divide uncontrollably. Early warning signs and symptoms of the cancer include difficulty urinating and needing to go to the toilet more regularly. But, how do doctors check for prostate cancer?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Contributors : Alvaro Aytes ; Antonina Mitrofanova ; Arianna Giacobe ; Cory Abate-ShenSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusAnalysis of transcriptome of FACS isolated cancer cells from prostate primary tumors and metastasis from NPK GEM models
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
A 70-year-old Caucasian male with pT3aN1Mx G3+4 prostate cancer underwent an open radical retropubic prostatectomy with lymphadenectomy without surgical complications. He experienced a slightly prolonged post-operative hospitalization (3 days) secondary to a reaction to an anesthesia study drug (tachycardia and drowsiness) that resolved after discontinuation of said drug and was subsequently discharged. Two weeks later, he was brought to the emergency department after the sudden onset of an acutely severe right groin pain and swelling that began that afternoon.
Source: Urology - Category: Urology & Nephrology Authors: Source Type: research
In this study, we identified pyruvate kinase M2 (PKM2) as a direct target of HCA by use of biochemical methods including affinity chromatography, drug affinity responsive target stability, and cellular thermal shift assay. PKM2 is up-regulated in multiple cancer types and is considered as a potential target for cancer therapy. HCA binds directly to PKM2 and selectively decreases the phosphorylation of PKM2 at Tyr105, indicating a potential anti-proliferative effect on prostate cancer cells.
Source: Cancer Letters - Category: Cancer & Oncology Authors: Tags: Original Articles Source Type: research
In this study, we sought to characterize the cost-effectiveness of SelectMDx in a population of U.S. men with elevated PSA.
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Source Type: research
CONCLUSIONS In prostate cancer, miR-99a-3p expression was associated with the Wnt and VEGF signaling pathways, which might inhibit the expression of PPP3CA or HYOU1. PMID: 29997385 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Conclusion: The inter-reader agreement for the PI-RADS v2 among the six readers with different experience is weak to moderate. Different experience levels affect the interpretation of MRI images. PMID: 29998885 [PubMed - in process]
Source: Chinese Medical Journal - Category: General Medicine Authors: Tags: Chin Med J (Engl) Source Type: research
Publication date: Available online 13 July 2018Source: European UrologyAuthor(s): Simon J. Crabb
Source: European Urology - Category: Urology & Nephrology Source Type: research
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