Assessing structure and function of myelin in cervical spondylotic myelopathy: Evidence of demyelination

Conclusion:
Our findings provide evidence of decreased myelin content in the spinal cord associated with impaired spinal cord conduction in patients with CSM. While conventional MRI are of great value to define the extent of cord compression, they show a limited correlation with functional deficits (i.e., delayed SSEPs). MWI provides independent and complementary readouts to spinal cord compression, with a high specificity to detect impaired conduction.

Source: Neurology - August 7, 2017 Category: Neurology Authors: Liu, H., MacMillian, E. L., Jutzeler, C. R., Ljungberg, E., MacKay, A. L., Kolind, S. H., Mädler, B., Li, D. K. B., Dvorak, M. F., Curt, A., Laule, C., Kramer, J. L. K. Tags: MRI, All Spinal Cord ARTICLE Source Type: research