Cumulative effects of single TMS pulses during beta-tACS are stimulation intensity-dependent

Single transcranial magnetic stimulation (TMS) pulses activate different components of the motor cortex neural circuitry in a stimulation intensity-dependent way and may lead to a cumulative increase of corticospinal excitability (CSE) during the same stimulation session. Furthermore, transcranial alternating current stimulation (tACS) has been shown to increase in a frequency-specific way the level of CSE probed by single-pulse TMS. The interaction of these two phenomena, i.e. cumulative increases and baseline shifts of CSE, and the involved neural circuitry has not been studied yet.

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - July 28, 2017 Category: Neurology Authors: Valerio Raco, Robert Bauer, Sandro Norim, Alireza Gharabaghi Source Type: research