Integrated Analysis of SNP, CNV and Gene Expression Data in Genetic Association Studies.

We present different methods to compare this gene list with the other three possible lists that result from the combinations of the following pairs of data: SNP genotype with gene expression, CNV genotype with gene expression, and SNP genotype with CNV genotype. The comparison is done using three different cancer datasets and two different methods of comparison. Our results show that integrating SNP, CNV, and gene expression data give better association results than integrating any pair of three data. PMID: 28685831 [PubMed - as supplied by publisher]
Source: Clinical Genetics - Category: Genetics & Stem Cells Authors: Tags: Clin Genet Source Type: research