Correlation among Inflammatory Cytokine Expression Levels, Degree of Disk Degeneration, and Predominant Clinical Symptoms in Patients with Degenerated Intervertebral Discs.

CONCLUSIONS: These results suggested that TNF-α and IL-6 play an important role in the pathophysiology of IVD degeneration at any stage, whereas NGF plays an important role during the early disease stages. Moreover, because TNF-α expression levels were significantly high in the LBP group, we propose that they are involved in LBP onset or progression. PMID: 28670416 [PubMed]

https://www.ncbi.nlm.nih.gov/pubmed/28670416?dopt=Abstract

Source: Asian Spine Journal - July 5, 2017 Category: Orthopaedics Tags: Asian Spine J Source Type: research

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