Pseudothrombotic microangiopathy and vitamin B12 deficiency in pernicious anemia.

Pseudothrombotic microangiopathy and vitamin B12 deficiency in pernicious anemia. Proc (Bayl Univ Med Cent). 2017 Jul;30(3):346-347 Authors: Veit K Abstract Vitamin B12 deficiency may present as pseudothrombotic microangiopathy. Pseudothrombotic microangiopathy is anemia, thrombocytopenia, and schistocytosis caused by vitamin B12 deficiency. Pseudothrombotic microangiopathy may be mistaken for microangiopathic hemolytic anemia, confounding appropriate treatment. Evaluation of lactate dehydrogenase, reticulocyte count, bilirubin, and platelet count are most helpful in differentiating pseudothrombotic microangiopathy from a true microangiopathic hemolytic anemia. A case of pseudothrombotic microangiopathy due to severe vitamin B12 deficiency is presented. PMID: 28670082 [PubMed - in process]
Source: Baylor University Medical Center Proceedings - Category: Universities & Medical Training Authors: Tags: Proc (Bayl Univ Med Cent) Source Type: research

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In conclusion, clinical characteristics of vitamin B12 deficiency are broad and nonspecific and may not be associated with anemia and increased mean corpuscular volume. Since different clinical characteristics can be seen without anemia, awareness and cautious approach are essential in order to avoid severe clinical disease, especially in children from underdeveloped countries. PMID: 31819326 [PubMed - in process]
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More News: Anemia | Bilirubin | Microangiopathic Hemolytic Anemia | Pernicious Anemia | Thrombocytopenia | Universities & Medical Training | Vitamin B12 | Vitamin B12 Deficiency | Vitamins