Using Multiple Pharmacovigilance Models Improves the Timeliness of Signal Detection in Simulated Prospective Surveillance

ConclusionsSimulation results indicate that, if the true model isnot known, an association can be detected in a more timely manner by first fitting a carefully selected set of exposure –risk models and then generating a signal as soon as any of the models considered yields a test statistic value below a predetermined testing threshold.
Source: Drug Safety - Category: Drugs & Pharmacology Source Type: research