Media Watch Antibiotic resistance: apocalypse soon?
Imagine a world in which a single pandemic disease is virulent and infectious enough to reduce the human population by over 99 ·9% in less than a year. That was the scenario presented in a new radio play by the well known thriller writer Val McDermid. Resistance was broadcast in three parts on BBC Radio 4 on March 3, 10, and 17, as part of its Dangerous Visions series of dystopian dramas.
The virus could mutate and spread.
[The Herald] Zimbabwe is among sub-Saharan African countries working tirelessly to meet the United Nations' 90-90-90 ambitious target to help end the HIV and Aids pandemic by 90 percent in 2020. On Monday, Zimbabweans woke up to news that seropositive people who are taking Abacavir -- a second line ARV drug -- are being given a week's supply of the drug instead of the traditional three months because of dwindled stocks.
Adhesion and invasion to epithelial cells and motility of extended-spectrum β-lactamase-producing Escherichia coli reveal ST131 superiority: a comparative in vitro study of extraintestinal pathogenic E. coli lineages. J Med Microbiol. 2017 Aug 22;: Authors: Kondratyeva K, Wollman A, Gerlitz G, Navon-Venezia S Abstract PURPOSE: Extended-spectrum β-lactamase (ESBL)-producing extraintestinal pathogenic Escherichia coli (ExPEC) sequence type ST131 is pandemic, and it is the major contributor to antibiotic resistance in E. coli. Despite its epidemiological superiority, the physiological reasons t...
guyen Currently licensed vaccines against the influenza A virus (IAV) need to be updated annually to match the constantly evolving antigenicity of the influenza virus glycoproteins, hemagglutinin (HA), and neuramidiase (NA). Attempts to develop universal vaccines that provide broad protection have resulted in some success. Herein, we have shown that a replication-deficient adenovirus expressing H5/M2e induced significant humoral immunity against the conserved HA stalk. Compared to the humoral responses induced by an inactivated influenza vaccine, the humoral responses induced by the adenovirus-vectored vaccine against ...
This report summarizes the recent epidemiological studies on vaccine in Japan as a prologue to the next six papers collected from the symposium. PMID: 28818469 [PubMed - in process]
U.S. Department of Health and Human Services, Office of the Assistant Secretary for Preparedness and Response. 08/15/2017 This 35-page document from TRACIE (Technical Resources, Assistance Center, Information Exchange) is intended to assist health care coalitions and their partners in assessing their preparedness for an influenza pandemic. It may also be used to orient the response as a pandemic begins. It starts with coalition-level activities that integrate information and issues from all disciplines, and provides the framework for integrated response. (PDF)
Conclusion These results suggest that 1,8-cineole (12.5 mg/kg) has a cross-protection against influenza virus, co-administered with inactivated influenza viral antigen in a mouse model. Graphical abstract
The 2009 H1N1 influenza pandemic, which involved a more pathogenic virus than seasonal influenza viruses, rapidly spread around the world and caused many deaths in humans. The members of the interferon-induced transmembrane (IFITM) protein family prevent viral replication and are crucial for defending the host cell against influenza A virus (IAV). Several studies suggest that the CC genotype at the single nucleotide polymorphism (SNP) rs12252 ofIFITM3 confers a genetic predisposition to pandemic influenza A in Europeans and Han Chinese, although one study in a British cohort failed to show an association. In order to exami...
(The Hebrew University of Jerusalem) Researchers at the Hebrew University of Jerusalem who studied health monitoring and communication during the recent Zika pandemic have proposed ways for health authorities to better contain future pandemics. Steps such as improving the readability of public health messages and announcing early can help authorities better contain pandemics, improve infection control and reduce public anxiety.
ConclusionsCompared with the prepandemic background incidence rate, the number of incident narcolepsy cases was 3.8‐fold and 2.8‐fold as high.