Increased connectivity of hub networks and cognitive impairment in multiple sclerosis

Conclusions:
In CI patients with MS, the DMN and FPN showed increased connectivity with the rest of the brain, while normal within- and between-network connectivity levels were maintained. These findings indicate that cognitive impairment in MS features disturbed communication of hub-rich networks, but only with the more peripheral (i.e., nonhub) regions of the brain.

Source: Neurology - May 29, 2017 Category: Neurology Authors: Meijer, K. A., Eijlers, A. J. C., Douw, L., Uitdehaag, B. M. J., Barkhof, F., Geurts, J. J. G., Schoonheim, M. M. Tags: fMRI, Multiple sclerosis ARTICLE Source Type: research