A Bayesian approach to the mixed-effects analysis of accuracy data in repeated-measures designs
We present logistic and probit mixed models that allow for random subject and item effects, as well as interactions between experimental conditions and both items and subjects in either one- or two-factor repeated-measures designs. The effect of experimental conditions on accuracy is assessed through Bayesian model selection and we consider two such approaches to model selection: (a) the Bayes factor via the Bayesian Information Criterion approximation and (b) the Watanabe-Akaike Information Criterion. Simulation studies are used to assess the methodology and to demonstrate its advantages over the more standard approach that consists of aggregating the accuracy data across trials within each condition and over the contemporary use of logistic and probit mixed models with model selection based on the Akaike Information Criterion. Software and examples in R and JAGS for implementing the analysis are available at https://v2south.github.io/BinBayes/.
PPAR-γ Agonists and Their Role in Primary Cicatricial Alopecia. PPAR Res. 2017;2017:2501248 Authors: Harnchoowong S, Suchonwanit P Abstract Peroxisome proliferator-activated receptor γ (PPAR-γ) is a ligand-activated nuclear receptor that regulates the transcription of various genes. PPAR-γ plays roles in lipid homeostasis, sebocyte maturation, and peroxisome biogenesis and has shown anti-inflammatory effects. PPAR-γ is highly expressed in human sebaceous glands. Disruption of PPAR-γ is believed to be one of the mechanisms of primary cicatricial alopecia (PCA) pathoge...
The president scored a 30 out of 30 on a cognitive assessment during his physical last week, his doctor told reporters
Conclusions: The hierarchical structure of the CART model provides a diagnostic algorithm linked with the risk of malignancy at every step of the procedure. It also provides guidance on the use of ancillary examinations as it goes by simple, human understandable rules.Acta Cytologica
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The risk for type 2 diabetes was reduced by almost half throughout their childbearing years for women who breastfed for 6 months or longer, a study found.Medscape Medical News
WASHINGTON (Reuters) - U.S. President Donald Trump passed a cognitive test and is in overall excellent health, but needs to lose 10 to 15 pounds (4.5 to 6.8 kg) by eating better and starting to exercise, the White House physician said on Tuesday.
CONCLUSION: Our findings do not support epicardial fat's beneficial effects on bone health, whereas general adiposity has an osteotropic effect. The association between EFT and BMC is through common genetic component factors. PMID: 29332861 [PubMed - as supplied by publisher]
CONCLUSIONS: Affected infants and toddlers in Fukushima suggested some growth disturbances and early adiposity rebound, which can cause obesity. The future growth of children affected by disasters should be followed carefully. PMID: 29332860 [PubMed - as supplied by publisher]
Los Angeles-based model Lauren Wasser, 29, lost her right leg in 2012 and had the other one amputated last week. 'Life is about to be so different, again!' she said in a post before the surgery.
In this study, eleven volunteers (aged 37-52) took six early-afternoon naps (30 minutes) in their occupational workplace, under two different conditions: control 'Naps' or 'Naps + RT' with a within-subjects design. Our results demonstrate that adding RT to naps changes sleep architecture, with a significant increase in the TST, mostly due to N2 sleep stage (and N3, to a lesser extent). Therefore, the deepening of short naps with RT involving hypnosis might be a successful non-pharmacological way to extend sleep duration and to deepen sleep in occupational settings. PMID: 29332862 [PubMed - as supplied by publisher]