Perioperative COX-2 and & beta;-adrenergic blockade improves metastatic biomarkers in breast cancer patients in a phase-II randomized trial.

Conclusions:<br /> <p>Perioperative inhibition of COX-2 and b-adrenergic signaling provides a safe and effective strategy for inhibiting multiple cellular and molecular pathways related to metastasis and disease recurrence in early-stage breast cancer.&nbsp.
PMID: 28490464 [PubMed - as supplied by publisher]

Source: Clinical Cancer Research - May 10, 2017 Category: Cancer & Oncology Authors: Shaashua L, Shabat-Simon M, Haldar R, Matzner P, Zmora O, Shabtai M, Sharon E, Allweis T, Barshack I, Hayman L, Arevalo JMG, Ma J, Horowitz M, Cole SW, Ben-Eliyahu S Tags: Clin Cancer Res Source Type: research