IUGR induced by maternal chronic inflammation: long-term effect on offspring ’s ovaries in rat model—a preliminary report

ConclusionsChronic maternal inflammation induced intrauterine growth restriction in offspring and a decrease in the proportion of follicles. This change might be due to premature apoptosis. These preliminary results suggest that maternal inflammation has a detrimental effect on the development of the female reproductive system of the offspring and thus, future fertility.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research