Long Term Outcomes of IV Glyburide In Patients 70 Years of Age or Under: Subgroup Analysis from the Phase II GAMES-RP Study of Patients with Large Hemispheric Infarction (S29.008)

Conclusions:This post-hoc analysis suggests that patients under 70, who may be at highest risk for poor outcomes secondary to edema after large hemispheric infarction, may have improved survival, better functional outcome and improved quality of life following treatment with IV glyburide. A prospective study is required in this population in order to definitively establish that IV glyburide can improve outcome.Study Supported by: Remedy Pharmaceuticals, NCT: 01794182Disclosure: Dr. Sheth has received personal compensation in an editorial capacity Current Treatment Options in Neurology. Dr. Sheth has received research support from Remedy Pharmaceuticals, Inc. Dr. Cheung has received personal compensation for activities with Remedy as a consultant. Dr. Cheung has received research support from IBM. Dr. Elm has received research support from Remedy. Dr. Hinson has nothing to disclose. Dr. Molyneaux has received research support from Remedy. Dr. Beslow has nothing to disclose. Dr. Sze has received research support from Remedy. Dr. Ostwaldt has received research support from Remedy. Dr. Kimberly has received research support from Remedy Pharmaceuticals, Inc.

Source: Neurology - April 17, 2017 Category: Neurology Authors: Sheth, K., Cheung, K., Elm, J., Hinson, H., Molyneaux, B., Beslow, L., Sze, G., Ostwaldt, A.-C., Kimberly, W. Tags: Cerebrovascular Disease and Interventional Neurology: Critical Care and Hemorrhage Source Type: research