Benchmarking a large regional UK HER2 testing service against current practice guidelines

Conclusions Single counting of HER2 FISH supported by a second rapid screen is safe and practicable within strict parameters. Any assessment of proximity of scores in double-scored cases should take into account the HER2 copy number, with greater spreads experienced at higher copy numbers. Centralising HER2 testing in a regional centre allows detailed audit of the entire analytical process.
Source: Journal of Clinical Pathology - Category: Pathology Authors: Tags: JCP Education Original article Source Type: research