Benchmarking a large regional UK HER2 testing service against current practice guidelines
Conclusions
Single counting of HER2 FISH supported by a second rapid screen is safe and practicable within strict parameters. Any assessment of proximity of scores in double-scored cases should take into account the HER2 copy number, with greater spreads experienced at higher copy numbers. Centralising HER2 testing in a regional centre allows detailed audit of the entire analytical process.
Source: Journal of Clinical Pathology - Category: Pathology Authors: Thomas, J., Loane, J., Matthews, R., Maxwell, S., Ingman, T., Beesley, M., Ferrigan, L. Tags: JCP Education Original article Source Type: research
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