Therapeutic potential of chemically modified siRNA: Recent trends

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Ribose Modifications

Phosphate Backbone Modifications

Nucleobase Modifications

Modification to the Termini and Conjugate groups

siRNA Binding

Source: Chemical Biology and Drug Design - April 5, 2017 Category: Biology Authors: Chelliah Selvam, Daniel Mutisya, Sandhya Prakash, Kasturi Ranganna, Ramasamy Thilagavathi Tags: Review Source Type: research