The adequate corpus luteum: miR-96 promotes luteal cell survival and progesterone production.

Conclusions: miR-96 targets FOXO1 to regulate luteal development through effects on cell survival and steroid production. The miR-183-96-182 cluster could provide a novel target for the manipulation of luteal function.
PMID: 28368475 [PubMed - as supplied by publisher]

Source: The Journal of Clinical Endocrinology and Metabolism - March 20, 2017 Category: Endocrinology Authors: Mohammed BT, Sontakke SD, Ioannidis J, Duncan WC, Donadeu FX Tags: J Clin Endocrinol Metab Source Type: research