Reversibility of Vasalgel ™ male contraceptive in a rabbit model

ConclusionsVasalgel ’s prevention of sperm transport for 14 months was reversed through an intravasal injection of sodium bicarbonate. Post-reversal sperm concentrations and motility returned to baseline levels during the six-month follow up. Residual material in the vas lumen or compromised epididymal and vas defere ns function may be resulting in reduced forward progression and loss of acrosomes during transit through the vas. Reduced forward progression and the lack of normal acrosomes strongly suggest impaired sperm function.
Source: Basic and Clinical Andrology - Category: Urology & Nephrology Source Type: research