Glucocorticoid-induced leucine zipper may play an important role in icariin by suppressing osteogenesis inhibition induced by glucocorticoids in osteoblasts.

CONCLUSIONS: These results indicate that the GILZ-mediated osteogenic signal pathway is involved in the osteogenic effect induced by icariin.
PMID: 28363169 [PubMed - as supplied by publisher]

Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - March 28, 2017 Category: Drugs & Pharmacology Authors: Lin Z, Jiang ZL, Chen LH, Sun Y, Chen SZ, Zhou P, Xia AX, Jin H, Zhu YW, Chen DY Tags: Biomed Pharmacother Source Type: research