Self-confessed former 'bad boy' donates kidney to cystic fibrosis sufferer

Wesley Joyce decided to 'change his life' after the plight of 34-year-old Sally-Anne Grainger, from Worcestershire, who went into renal failure after having to take strong medication following a double lung transplant in 2009.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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ConclusionsThe current study indicates that a history of OSAS/CSAS, myocardial infarction and BMI > 30 might be related to ICU admission in influenza patients. Second, ICU patients develop more pulmonary co-infections. Last, (pre-existent) renal failure and diabetes mellitus are more often observed in non-survivors.
Source: Journal of Critical Care - Category: Gastroenterology Source Type: research
Publication date: February 2019Source: Biomedicine &Pharmacotherapy, Volume 110Author(s): Nahid Aboutaleb, Hosein Jamali, Maryam Abolhasani, Hamidreza Pazoki ToroudiAbstractRenal ischemia/reperfusion (I/R) injury following kidney transplantation has been found to be a great clinical problem owing to initiation of acute inflammatory responses and subsequently rapid loss of kidney function. It is well known that lavender oil exhibits an extensive spectrum of pharmacological and biochemical activities. The purpose of this study was to clarify molecular targets of lavender in treatment of this disease.Male Wistar rats weig...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
In conclusion, ALBI score demonstrated significant predictive capabilities for survival in patients with compensated cirrhosis resected for hepatocellular carcinoma. PMID: 30431722 [PubMed - in process]
Source: Acta Clinica Croatica - Category: General Medicine Tags: Acta Clin Croat Source Type: research
DiscussionThe overall results suggest that non-commercial, simple media formulations with extended storage intervals at 2–10°C temperatures are capable of retaining the characteristics of clinical-grade HUC-MSCs. The above findings led us to use RL (1% HSA) media at 2–10°C for transport and storage in the HUC-HEART Trial; 23 patients received HUC-MSCs by August 2018; no adverse effects were noted related to cell processing and transplantation.
Source: Cytotherapy - Category: Cytology Source Type: research
Conclusions Clinicians treating individuals with spina bifida should be aware of the potential for earlier mortality in individuals with myelomeningocele, hydrocephalus, and Chiari II malformation, especially with regard to infection, respiratory failure, renal failure, shunt malfunction, and cancer. To Claim CME Credits Complete the self-assessment activity and evaluation online at CME Objectives Upon completion of this article, the reader should be able to: (1) Discuss the importance of recognizing co-morbidities in adult individuals with spina bifida; (2) Describe secondary co...
Source: American Journal of Physical Medicine and Rehabilitation - Category: Rehabilitation Tags: Original Research Articles CME Article . 2018 Series . Number 12 Source Type: research
Publication date: January 2019Source: Journal of Functional Foods, Volume 52Author(s): Meimei Wang, Hang Ma, Zhaoxing Li, Yang Yu, Liangyu Liu, Xuegang Li, Xiaoli YeAbstractThe aim of this study was to explore the inhibitory effects of SPG-56 and intestinal microbes on the progression of colorectal cancer (CRC). An in-vivo model of CRC was generated by transplanting BALB/c nude mice with HCT-116 cells and tumor progression was monitored after treatment with SPG-56 (150 mg/kg), Lactobacillus fermentum (2 × 108 cfu/0.2 ml) + SPG-56 (150 mg/kg) and short-chain fatty acids (SCFAs, 20 mM/0.2 ml). All thr...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
Alcohol-associated cirrhosis (AC) contributes up to 50% of the overall cirrhosis burden in the United States. AC is typically a comorbid condition in association with alcohol-use disorder. AC is often coexistent with other conditions. Several noninvasive methods are available to assist in recognizing the presence of AC. The natural history of AC is governed by the patients continued drinking or abstinence. All treatment starts with abstinence. After decompensation, the progression to acute-on-chronic liver failure heralds death. When patients who have deteriorated are declined liver transplant, palliative care should be considered.
Source: Clinics in Liver Disease - Category: Gastroenterology Authors: Source Type: research
Alcoholic liver disease is a serious and increasing contributor to the global liver disease burden. Extensive selection criteria, including a minimum abstinence period, has previously been used to secure good outcomes but new research questions the effectiveness of abstinence periods and has recommended changes in integrated alcohol use treatment to effectively prevent relapse. Patients have unique health concerns, including posttransplantation risks of malignancy and metabolic complications, but overall very good long-term outcomes. Severe alcoholic hepatitis has been increasingly treated with early transplantation withou...
Source: Clinics in Liver Disease - Category: Gastroenterology Authors: Source Type: research
Objectives: To identify, appraise, and synthesize current evidence to determine whether early enteral nutrition alters patient outcomes from major burn injury. Data Sources: Medline, Embase, and the China National Knowledge Infrastructure were searched. The close out date was May 1, 2018. Study Selection: Early enteral nutrition was defined as a standard formula commenced within 24 hours of injury or admission to ICU or burn unit. Comparators included any form of nutrition support “except” early enteral nutrition. Only randomized controlled trials reporting patient-centered outcomes were eligible for in...
Source: Critical Care Medicine - Category: Emergency Medicine Tags: Review Articles Source Type: research
Nontuberculous mycobacteria (NTM) are important emerging cystic fibrosis (CF) pathogens, with estimates of prevalence ranging from 6% to 13%. Diagnosis of NTM disease in patients with CF is challenging, as the infection may remain indolent in some, without evidence of clinical consequence, whereas other patients suffer significant morbidity and mortality. Treatment requires prolonged periods of multiple drugs and varies depending on NTM species, resistance pattern, and extent of disease. The development of a disease-specific approach to the diagnosis and treatment of NTM infection in CF patients is a research priority, as ...
Source: Thoracic Surgery Clinics - Category: Cardiovascular & Thoracic Surgery Authors: Source Type: research
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