Thrombolysis with tPA 3-4.5 h after acute ischemic stroke in 5 hospital groups in Japan
Clinical data from Japan on the safety and realworld outcomes of alteplase (tPA) thrombolysis in the extended therapeutic window are lacking. The aim of this study was to assess the safety and real-world outcomes of tPA administered within 3-4.5 h of stroke onset. The study comprised consecutive acute ischemic stroke patients (n = 177) admitted across five hospitals between September 2012 and August 2014. Patients received intravenous tPA within
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Ryuta Morihara, Syoichiro Kono, Toru Yamashita, Kentaro Deguchi, Yasuhiro Manabe, Takako Yoshiki, Kenichi Kashihara, Satoshi Inoue, Hideki Kiriyama, Koji Abe Source Type: research