More on cardamonin and myeloma

After months of being too busy with other stuff, such as…life!, to do much research, I have been going through PubMed again, yaaaay, and this is one of the studies, published in 2015, that really caught my attention: goo.gl/YgMY8O You can actually read the full study online for free, at this link: goo.gl/muftiW As my blog title suggests, it’s about cardamonin, about which I actually wrote a brief post in February of 2011 (see http://margaret.healthblogs.org/other-alternative-treatments/cardamonin/). That post was based on a 2010 study, showing, and I quote, that “Cardamonin affects both the STAT3 and NF-kappaB pathways, which, as we know, are crucial for myeloma cell survival and proliferation. It also enhances the anti-MM activity of some conventional drugs used in the treatment of multiple myeloma: vincristine, doxorubicin, dexamethasone, bortezomib and thalidomide..[…] it also has a strong effect against COX2, Bcl-2, Bcl-xL, survivin, VEGF (angiogenesis).” Good stuff! Cardamonin is extracted from a plant of the ginger family, called Alpinia katsumadai (see photo), which is widely used in Chinese medicine to reduce inflammation, among other things. It also has antibacterial and antiviral effects… But, as far as we are concerned, the results of the 2015 study confirm those of the 2010 study, that is: cardamonin strongly inhibits myeloma cell activity and proliferation, and, at higher doses, kills the darn cells. Music to my ears...
Source: Margaret's Corner - Category: Cancer & Oncology Authors: Tags: Blogroll Alpinia katsumadai cardamonin myeloma Source Type: blogs