Androgen Receptor Splice Variants Are Not Substrates of Nonsense ‐Mediated Decay

CONCLUSIONThis study eliminates a possible mechanism of regulation of certain AR variants. Future research into the regulation of AR variants should focus on other mechanisms to better understand the origin of these variants and to possibly inhibit their expression for the resensitization of resistant cancers. Prostate. © 2017 Wiley Periodicals, Inc.

Source: The Prostate - February 22, 2017 Category: Urology & Nephrology Authors: Atinuke S. Ajiboye, David Esopi, Srinivasan Yegnasubramanian, Samuel R. Denmeade Tags: Original Article Source Type: research