An adaptive variant of TRIB2, rs1057001, is associated with higher expression levels of thermogenic genes in human subcutaneous and visceral adipose tissues

An obesity-related single-nucleotide polymorphism (SNP) of the Tribbles pseudokinase 2 gene (TRIB2) was shown to have underwent adaptive evolution in the last glacial period, suggesting a selective advantage of t...

Source: Journal of Physiological Anthropology - February 17, 2017 Category: Physiology Authors: Kazuhiro Nakayama and Sadahiko Iwamoto Source Type: research