Infectious Zika virus in vaginal secretions from an HIV-infected woman, France, August 2016.

Infectious Zika virus in vaginal secretions from an HIV-infected woman, France, August 2016. Euro Surveill. 2017 Jan 19;22(3): Authors: Penot P, Brichler S, Guilleminot J, Lascoux-Combe C, Taulera O, Gordien E, Leparc-Goffart I, Molina JM Abstract A woman with controlled HIV infection developed in late August 2016 a pruritic rash with fever and conjunctival hyperaemia after a trip to the French Caribbean islands. On day 3 after symptom onset, Zika virus RNA was detected in plasma, urine and vaginal samples with respective viral loads of 3.8, 6.1 and 5.3 log copies/mL. Notably, we demonstrated the presence of infectious Zika virus particles in the vaginal samples by isolation in cell culture. PMID: 28128730 [PubMed - in process]
Source: Euro Surveill - Category: Infectious Diseases Authors: Tags: Euro Surveill Source Type: research

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Publication date: Available online 18 November 2019Source: The LancetAuthor(s): Oliver J Brady, Simon I Hay
Source: The Lancet - Category: General Medicine Source Type: research
The ability of self-replicating oncolytic viruses (OVs) to preferentially infect and lyse cancer cells while stimulating anti-tumor immunity of the host strongly indicates its value as a new field of cancer therapeutics to be further explored. The emergence of Zika virus (ZIKV) as a global health threat due to its recent outbreak in Brazil has caught the attention of the scientific community and led to the discovery of its oncolytic potential for the treatment of glioblastoma multiforme (GBM), the most common and fatal brain tumor with poor prognosis. Herein, we evaluate the neurotropism of ZIKV relative to the receptor ty...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
The explosive rise in cases of Zika virus infection is of concern worldwide. Stay up-to-date here.
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Resource Center Source Type: news
;vio G. da Fonseca Dengue is currently one of the most important arbovirus infections worldwide. Early diagnosis is important for disease outcome, particularly for those afflicted with the severe forms of infection. The goal of this work was to identify conserved and polymorphic linear B-cell Dengue virus (DENV) epitopes that could be used for diagnostic purposes. To this end, we aligned the predicted viral proteome of the four DENV serotype and performed in silico B-cell epitope mapping. We developed a script in Perl integrating alignment and prediction information to identify potential serotype-specific epitopes. We ...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Synfacts 2019; 15: 1375- DOI: 10.1055/s-0039-1691267 © Georg Thieme Verlag Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Full text
Source: Synfacts - Category: Chemistry Tags: Synthesis of Materials and Unnatural Products Source Type: research
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Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
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Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
Lu Lu Recently, Zika virus (ZIKV) has attracted much attention in consideration of its association with severe neurological complications including fetal microcephaly. However, there are currently no prophylactic vaccines or therapeutic drugs approved for clinical treatments of ZIKV infection. To determine the potential anti-ZIKV inhibitors, we screened a library of clinical drugs with good safety profiles. Erythromycin estolate (Ery-Est), one of the macrolide antibiotics, was found to effectively inhibit ZIKV infection in different cell types and significantly protect A129 mice from ZIKV-associated neurological sign...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
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Source: Journal of Infection - Category: Infectious Diseases Authors: Tags: RESEARCH ARTICLE Source Type: research
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Source: Journal of Vector Ecology - Category: Biology Authors: Tags: Original Article Source Type: research
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