Glucagon ‐like peptide‐1 receptor expression on human eosinophils and its regulation of eosinophil activation

Conclusion and Clinical RelevanceGlucagon‐like peptide‐1 receptor is expressed on human eosinophils and neutrophils. A GLP‐1 analog attenuates LPS‐stimulated eosinophil activation. GLP‐1 agonists may have additional adjunctive indications in treating persons with concomitant type 2 diabetes mellitus and asthma.

Source: Clinical and Experimental Allergy - January 27, 2017 Category: Allergy & Immunology Authors: P. D. Mitchell, B. M. Salter, J. P. Oliveria, A. El ‐Gammal, D. Tworek, S. G. Smith, R. Sehmi, G. M. Gauvreau, M. Butler, P. M. O'Byrne Tags: Original Article Source Type: research