Sperm quality and paternal age: effect on blastocyst formation and pregnancy rates

ConclusionsThese results allow adjusting our strategies of fertilization technique and embryo transfer. In the case of severe oligospermia, transfer should be carried out at the cleaved embryo stage (day 2 –3) due to the very low blastulation rate. When the man is older than 51 years, couples should be aware of the reduced success rate, especially if the woman is older than 37 years. Finally, promising research avenues should be explored, such as the quantification of free sperm DNA, to optimize t he selection of male gametes.

Source: Basic and Clinical Andrology - January 20, 2017 Category: Urology & Nephrology Source Type: research