Single woman granted fertility treatment on NHS after having ovaries removed

Single woman Claire Danes, 41, from Manchester, who was granted IVF funding on the NHS finally has a baby after suffering three miscarriages and being left infertile at age 21.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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The objective of this study was to demonstrate a markedly enlarged isthmocele, that resulted in the miscarriage of a 12-week IVF twin pregnancy.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Source Type: research
Objective: To evaluate whether a novel technique of hysteroscopic metroplasty (PALPATOR-metroplasty) may maximize reproductive outcomes in women with partial or complete uterine septum (US) by achieving an optimal fundal thickness.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Source Type: research
This study investigated the quality and quantity of eggs and embryos as well as the clinical pregnancy outcome in young infertile women with diminished ovarian reserve (DOR) after in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI). MATERIAL AND METHODS We retrospectively reviewed records of 4285 infertile women and divided them into 3 groups according to age and ovarian reserve: young women with normal ovarian reserve (n=1695), young women with DOR (n=1121), and older women with DOR (n=1469). RESULTS In young women with DOR, the proportion of high-quality embryos was significantly higher than in older women...
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
ConclusionHysteroscopic surgery using cold graspers combined with electric loop by the HEOS is feasible and effective for treatment of DUL as it preserves the uterus and yields favorable reproductive outcomes. The cold surgery and fenestration method minimize electrical and thermal damage to the endometrium surrounding the myoma, consequently reducing surgical risks.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
CONCLUSIONS: Given its potential to reduce the miscarriage rate, LT4 supplementation is recommended for infertile women with SCH and/or TAI who are undergoing IVF/ICSI. However, additional population-based RCTs are needed to confirm this recommendation. PMID: 30249251 [PubMed - in process]
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Tags: Reprod Biol Endocrinol Source Type: research
ConclusionIn light of connecting etiological link between infertility and RM as reviewed in this study, interrogating the oocyte-specific genes with suspected roles in reproductive biology, in cases of unexplained RM, may open new possibilities in widening our understanding of RM pathophysiology.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research
ni ME Abstract Context: There is increasing evidence for MIS/AMH physiologic activity in the human uterus, so it is relevant to study how MIS/AMH levels impact pregnancy. Objective: To investigate the association of MIS/AMH levels with risk of adverse obstetric outcomes. Design: Retrospective cohort study. Setting: Academic fertility center. Patients: Women who became pregnant through in vitro fertilization (IVF) between January 2012-October 2016. Exclusion criteria were: oocyte donation, gestational carrier, multiple gestation, miscarriage before 20 weeks, medically indicated preterm deliverie...
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research
The thyroid is critical in metabolism, steroidogenesis and development. While treatment of thyroid abnormalities in reproductive-aged women is universally accepted, the threshold for thyroid stimulating hormone (TSH) is still debated. The American Society for Reproductive Medicine suggests 2.5 mIU/L while the American Thyroid Association recommends 4.12 mIU/L. Fertility, particularly ovulation, implantation and miscarriage risk, is impaired by thyroid dysfunction, but there is limited understanding of artificial reproductive technologies (ART) outcomes in euthyroid women.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Poster session Source Type: research
Increased serum C-reactive protein (CRP) levels have recently been reported to reduce fecundity in healthy eumenorrheic women with a history of 1-2 pregnancy losses. 1 As subclinical systemic inflammation may impede maternal immune tolerance, implantation and embryonic development might be compromised. Inflammation could, thus, also serve as a causative factor for the substantial proportion of miscarriages that reveal normal karyotypes after analysis of products of conception (POCs). To evaluate in infertile women the relationship between pre-pregnancy CRP levels and POC karyotype was the objective of this study.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Poster session Source Type: research
Ovulation Induction with IUI is a common first step in the treatment of infertility given its lower cost and ease of implementation compared to IVF. Disadvantages include lower pregnancy rates and thus longer time to conception. PGT-A provides the advantage of lower miscarriage rates (SAB). We sought to compare the pregnancy outcomes and cost per cycle of IUI and IVF/ PGT-A.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Poster session Source Type: research
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