Proteomic Investigation of Dermal Fibroblasts Isolated from Affected and Unaffected Skin Samples from Patients with Limited Cutaneous Systemic Sclerosis: 2 Distinct Entities?

CONCLUSION: Consistent with previous studies, these findings are important for 2 reasons: first, because they reveal the opposite behavior of dermal fibroblasts in the unaffected and affected skin areas of the same patient with lcSSc; second, because they demonstrate the histological/histochemical similarities between unaffected skin from patients with lcSSc and healthy control skin. PMID: 27909082 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/27909082?dopt=Abstract

Source: J Rheumatol - November 30, 2016 Category: Rheumatology Authors: Corallo C, Santucci A, Bernardini G, Figura N, Leoncini R, Riolo G, Montella A, Chirico C, Nuti R, Giordano N Tags: J Rheumatol Source Type: research