Low Level of Blood CD4+ T-Cells Is An Independent Predictor of Inferior Progression Free Survival in Diffuse Large B-Cell Lymphoma

Immune cell subsets in blood of patients with diffuse large B cell lymphoma prior to therapy were characterized by flow cytometry and levels of various T-cell types and NK cells correlated with eventual outcomes. High absolute levels of CD4 cells in blood correlated with better progression free survival, and to a lesser extent overall survival, independent of age and IPI.

Source: Clinical Lymphoma, Myeloma and Leukemia - November 28, 2016 Category: Hematology Authors: Julia Judd, Essel Dulaimi, Tianyu Li, Michael M. Millenson, Hossein Borghaei, Mitchell R. Smith, Tahseen Al-Saleem Tags: Original Study Source Type: research