Altered Expression of Long Noncoding RNAs in Blood After Ischemic Stroke and Proximity to Putative Stroke Risk Loci [Clinical Sciences]

Conclusions—This study provides evidence of altered and sexually dimorphic lncRNA expression in peripheral blood of patients with stroke compared with that of controls and suggests that lncRNAs have potential for stroke biomarker development. Some regulated lncRNA could regulate some previously identified putative stroke-risk genes.

Source: Stroke - November 27, 2016 Category: Neurology Authors: Cheryl Dykstra-Aiello, Glen C. Jickling, Bradley P. Ander, Natasha Shroff, Xinhua Zhan, DaZhi Liu, Heather Hull, Miles Orantia, Boryana S. Stamova, Frank R. Sharp Tags: Biomarkers, Women, Gene Expression & Regulation, Ischemic Stroke Original Contributions Source Type: research