[Comment] Unravelling mucosal immunity to poliovirus

From an immunological perspective, the battle to eradicate polio is one of blood and guts. Induction of circulating poliovirus antibodies in blood is essential to block the spread of viruses to the CNS and thereby protect against paralytic disease. However, as eradication draws closer, the induction of immunity in the gut mucosa is becoming an ever-greater concern. Mucosal immunity is key to halting the spread of poliovirus from person to person, and thereby condemning the virus to extinction.
Source: The Lancet Infectious Diseases - Category: Infectious Diseases Authors: Tags: Comment Source Type: research