Lack of Siglec-7 expression identifies a dysfunctional natural killer cell subset associated with liver inflammation and fibrosis in chronic HCV infection

Conclusions
These findings identify Siglec-7neg NK cells as a dysfunctional subpopulation associated with severe liver disease in chronic HCV infection.

Source: Gut - November 8, 2016 Category: Gastroenterology Authors: Varchetta, S., Mele, D., Lombardi, A., Oliviero, B., Mantovani, S., Tinelli, C., Spreafico, M., Prati, D., Ludovisi, S., Ferraioli, G., Filice, C., Aghemo, A., Lampertico, P., Facchetti, F., Bernuzzi, F., Invernizzi, P., Mondelli, M. U. Tags: Hepatology Source Type: research