NCI Center to Reduce Cancer Health Disparities Spotlights Center for Personalized Cancer Therapy

UMass Boston and DF/HCC have a U54 Partnership grant with NCI/CRCHD to develop life sciences and CPCT on the UMass Boston campus. Read the Spotlight:
Source: DF/HCC: Latest News - Category: Cancer & Oncology Tags: Announcements Source Type: news

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Not all that long ago, chemotherapy was the only option to treat most advanced (metastatic) cancers. Because these drugs work by destroying rapidly dividing cells, they harm some healthy cells — such as hair follicles — as well as cancer cells. In the past two decades, cancer treatment has been transformed by targeted drugs and the emergence of chemotherapy. Targeted drugs are designed to home in on specific genes or proteins that are altered or overexpressed on cancer cells. Immunotherapy has been very successful for certain types of advanced cancers, such as lung, bladder, and skin cancers. One form of immuno...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Cancer Immunotherapy Managing your health care Source Type: blogs
Fangyu Chen, Liuwei Chen, Qin Qin, Xinchen Sun
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Qingxin Mu, Bing Yan
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
ConclusionPatients with probably high anxiety levels (younger age, low education level, and those appearing for frightening procedures) should receive  extra careful clarification and treatment support such as a psycho-oncologist.
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
Almost everyone experiences bad breath once in a while. But for some people, bad breath is a daily problem, and they struggle to find a solution. Approximately 30% of the population complains of some sort of bad breath. Halitosis (Latin for “bad breath”) often occurs after a garlicky meal or in the morning after waking. Other causes of temporary halitosis include some beverages (including alcoholic drinks or coffee) and tobacco smoking. Some people may not be aware of their own halitosis and learn about it from a relative, friend, or coworker, causing some degree of discomfort and distress. In severe cases, bad...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Dental Health Source Type: blogs
AbstractBreast cancer has developed to become the leading type of cancer in females. For this study, 80 women were examined after chemotherapy for breast cancer and compared to 80 healthy age-matched women. This cross-sectional study comprised a dental examination with number of teeth, caries frequency (DMFT) and the presence of periodontal diseases (PSI). With the help of X-rays (OPG), the number of root canal fillings and apical lesions (LEO/LPO) were recorded. Furthermore, the education level, body mass index (BMI), smoking habits and general health conditions were recorded. All women completed questionnaires on oral he...
Source: Odontology - Category: Dentistry Source Type: research
Publication date: Available online 18 January 2019Source: Materials Science and Engineering: CAuthor(s): Dnyaneshwar Kalyane, Nidhi Raval, Rahul Maheshwari, Vishakha Tambe, Kiran Kalia, Rakesh K. TekadeAbstractIn tumorous tissues, the absence of vasculature supportive tissues intimates the formation of leaky vessels and pores (100 nm to 2 μm in diameter) and the poor lymphatic system offers great opportunity to treat cancer and the phenomenon is known as Enhanced permeability and retention (EPR) effect. The trends in treating cancer by making use of EPR effect is increasing day by day and generate multitudes of poss...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
The physical and psychological side effects of breast cancer therapies can have substantial impact on survivors' physical and social functioning. Roughly half of the more than 3 million Americans alive with a history of breast cancer report adverse, function-degrading sequelae related to their oncologic treatments. Care delivery models for the timely delivery of rehabilitation services have been proposed yet limitedly vetted or implemented. These include the prospective surveillance model, procedure-linked referrals, survivorship care plans, and risk stratification. Patients' capacity to engage in the rehabilitative proces...
Source: American Journal of Physical Medicine and Rehabilitation - Category: Rehabilitation Tags: Literature Review Source Type: research
CONCLUSIONS TCL-based immunotherapy has discrepant anti-tumor efficiency in different TNBC cell lines by PDL-1/PD interaction, providing the theoretical basis of TCL-based immunotherapy in TNBC. PMID: 30653481 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
by Craig Klugman, Ph.D. Jump to The Resident (Season 2; Episode 10): What would you do doctor?a>;Jump to The Good Doctor (Season 1; Episode 11): Ignoring patient rights; unnecessary risks; crisis planning; Jump to New Amsterdam (Season 1; Episode 11): Superutilizers and racism; Jump to Chicago Med (Season 4; Episode 11): Triage, gestational surrogacy conflicts; ends justifies the means The Resident (Season 2; Episode 10): What would you do doctor? As Hunter is released from prison on murder charges for killing patients with unneeded cancer therapy (sometimes on people without cancer), one of her victims is in the ED wit...
Source: - Category: Medical Ethics Authors: Tags: BioethicsTV Conflict of Interest Decision making End of Life Care Featured Posts Informed Consent professional ethics Public Health Reproductive Ethics Source Type: blogs
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