Smoking Tied to Worse Lupus, Arthritis (CME/CE)

(MedPage Today) -- Worse patterns of disease for both rheumatoid arthritis and systemic lupus erythematosus were seen among patients who were smokers, and the risks actually increased after quitting for those with lupus, Swedish researchers reported.
Source: MedPage Today Geriatrics - Category: Geriatrics Source Type: news

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This study suggests that the hsa_circ_0044235 in peripheral blood may be a potential biomarker of patients with RA. This article is protected by copyright. All rights reserved. PMID: 30216431 [PubMed - as supplied by publisher]
Source: Clinical and Developmental Immunology - Category: Allergy & Immunology Authors: Tags: Clin Exp Immunol Source Type: research
Lupus and arthritis are separate conditions. However, arthritis is one of the most common symptoms of lupus. There may also be a genetic link between rheumatoid arthritis and lupus. In this article, we look at the connection between lupus and arthritis, along with the causes, symptoms, and treatment of the conditions.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Rheumatoid Arthritis Source Type: news
In this study, we investigated the clinical relevance and functional significance of TSP-1 and ATSA in SLE patients. Serum levels of TSP-1 and ATSA were measured by ELISA in 138 adult SLE patients and 60 healthy controls. Blood cell counts, rheumatoid factor (RF), immunoglobulins, erythrocyte sedimentation rate (ESR), complements, and SLE-related autoantibodies were measured by standard laboratory techniques. Disease activity was assessed by systemic lupus erythematosus disease activity index (SLEDAI). TSP-1 concentrations were significantly lower in SLE patients compared with those in healthy controls. A significant diffe...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
In conclusion, IgA-aPL is not rare in SLE (16%) and IgA-aPL analysis may have additional value among SLE cases with suspected APS testing negative for other isotypes of aPL and LA. PMID: 30208508 [PubMed - as supplied by publisher]
Source: Clinical and Developmental Immunology - Category: Allergy & Immunology Authors: Tags: Clin Exp Immunol Source Type: research
Authors: Maryam S, Atabati E, Yalda R PMID: 30197705 [PubMed]
Source: Open Rheumatology Journal - Category: Rheumatology Tags: Open Rheumatol J Source Type: research
Publication date: Available online 11 September 2018Source: Autoimmunity ReviewsAuthor(s): Kassem Sharif, Howard Amital, Yehuda Shoenfeld, MaACRAbstractAutoimmune diseases are a group of heterogeneous condition that occur secondary to the intrinsic loss of tolerance to self- antigens. In genetically susceptible individuals, the complex interplay of environmental factors and epigenetic deregulations have been proposed to drive disease etiopathogenesis. Various environmental variables have been identified including viral infections, exposure to pollutants, stress and dietary factors. Sodium, a major constituent of salt is es...
Source: Autoimmunity Reviews - Category: Allergy & Immunology Source Type: research
Thrombotic microangiopathies are heterogeneous disorders characterized by microangiopathic hemolytic anemia with thrombocytopenia and renal injury. There are a variety of causes, including metabolic disorders, infections, medications, complement disorders, pregnancy, malignancy, and autoimmune disorders. This review focuses on renal thrombotic microangiopathy in the setting of rheumatologic diseases. Systemic lupus erythematosus is the most common autoimmune disease associated with thrombotic microangiopathy. Other etiologies include scleroderma renal crisis and antiphospholipid antibody syndrome, which can be primary or s...
Source: Rheumatic Disease Clinics of North America - Category: Rheumatology Authors: Source Type: research
Abstract The rheumatic diseases, which include systemic lupus erythematosus, rheumatoid arthritis, Beh çet's disease, scleroderma, and ankylosing spondylitis, are characterized by involvement of connective tissue, with multiple manifestations. In those diseases, there can be involvement of the peripheral or central nervous system, and that involvement can be primary, presenting as a major feature of the clinical presentation, or secondary, as an effect of the drugs used in order to control a given disease or its complications. Knowledge of the wide variety of imaging findings is crucial to the diagnosis of a rheumat...
Source: Radiologia Brasileira - Category: Radiology Source Type: research
Abstract The rheumatic diseases, which include systemic lupus erythematosus, rheumatoid arthritis, Beh çet's disease, scleroderma, and ankylosing spondylitis, are characterized by involvement of connective tissue, with multiple manifestations. In those diseases, there can be involvement of the peripheral or central nervous system, and that involvement can be primary, presenting as a major feature of the clinical presentation, or secondary, as an effect of the drugs used in order to control a given disease or its complications. Knowledge of the wide variety of imaging findings is crucial to the diagnosis of a rheumat...
Source: Radiologia Brasileira - Category: Radiology Source Type: research
Abstract The rheumatic diseases, which include systemic lupus erythematosus, rheumatoid arthritis, Beh çet's disease, scleroderma, and ankylosing spondylitis, are characterized by involvement of connective tissue, with multiple manifestations. In those diseases, there can be involvement of the peripheral or central nervous system, and that involvement can be primary, presenting as a major feature of the clinical presentation, or secondary, as an effect of the drugs used in order to control a given disease or its complications. Knowledge of the wide variety of imaging findings is crucial to the diagnosis of a rheumat...
Source: Radiologia Brasileira - Category: Radiology Source Type: research
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