Restoration of Hydrogen Sulfide Production in Diabetic Mice Improves Reparative Function of Bone Marrow Cells.

CONCLUSIONS: -Decreased CSE-mediated H2S bioavailability is an underlying source of BMC dysfunction in diabetes. Our data indicate that H2S and overexpression of CSE in diabetic BMCs may rescue their dysfunction and open novel avenues for cell-based therapeutics of CLI in diabetic patients. PMID: 27660293 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/27660293?dopt=Abstract

Source: Circulation - September 21, 2016 Category: Cardiology Authors: Cheng Z, Garikipati V, Nickoloff E, Wang C, Polhemus DJ, Zhou J, Benedict C, Khan M, Verma SK, Rabinowitz JE, Lefer D, Kishore R Tags: Circulation Source Type: research

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