Isotretinoin treatment in a patient with known peanut allergy and positive IgE test results for soybean

Isotretinoin is a retinoid that is approved by the US Food and Drug Administration for the treatment of acne vulgaris and used off label for other dermatologic conditions, including hidradenitis suppurativa (HS). Isotretinoin decreases comedones and sebum production, influences cell-cycle progression, and reduces inflammation.1 Prescribing information leaflets state that oral isotretinoin is contraindicated in patients with known allergy to isotretinoin, peanut, or soya.2 Soybean oil is found within the capsules; thus, patients with peanut allergy might be considered at risk because of the known cross-reactivity between soybean and peanut.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letter Source Type: research