Genome-wide analyses of HTLV-1aD strains from Cape Verde, Africa.

Genome-wide analyses of HTLV-1aD strains from Cape Verde, Africa. Mem Inst Oswaldo Cruz. 2016 Sep;111(9):594-6 Authors: Zanella L, Pina-Araujo I Id, Morgado MG, Vicente AC Abstract We characterised and reported the first full-length genomes of Human T-cell Lymphotropic Virus Type 1 subgroup HTLV-1aD (CV21 and CV79). This subgroup is one of the major determinants of HTLV-1 infections in North and West Africa, and recombinant strains involving this subgroup have been recently demonstrated. The CV21 and CV79 strains from Cape Verde/Africa were characterised as pure HTLV-1aD genomes, comparative analyses including HTLV-1 subtypes and subgroups revealed HTLV-1aD signatures in the envelope, pol, and pX regions. These genomes provide original information that will contribute to further studies on HTLV-1a epidemiology and evolution. PMID: 27653363 [PubMed - in process]
Source: Memorias do Instituto Oswaldo Cruz - Category: Infectious Diseases Authors: Tags: Mem Inst Oswaldo Cruz Source Type: research