Acute and chronic infections with nonprimate hepacivirus in young horses

AbstractThe recently discovered nonprimate hepacivirus (NPHV) naturally infects horses and is the closest known homolog of hepatitis C virus to date. Within a follow-up study acute field infections were monitored in four young Thoroughbred horses until the ages of 12 –13 months. Serum samples were analyzed for the presence of NPHV RNA and anti-NPHV NS3 antibodies and liver specific parameters were evaluated. The four young horses were not able to clear infection, but remained chronically infected for the entire monitored time period despite the presence of NP HV specific antibodies.
Source: Veterinary Research - Category: Veterinary Research Source Type: research

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Authors: Clipa A, Şuţa M, Dumitru E, Muflic L PMID: 31803280 [PubMed]
Source: Journal of Medicine and Life - Category: General Medicine Tags: J Med Life Source Type: research
Authors: Craxì L Abstract In recent years, the debate on ethical issues related to hepatitis C virus therapies has been focused on the problem of drug prices and access to therapies. Nonetheless, the goal of hepatitis C virus eradication set by the World Health Organization in 2016 is raising new ethical issues, since governments are faced with a new challenge: reaching through screening, diagnosis and treatment a large amount of subjects with undiagnosed hepatitis C infection. National governments, especially high-income countries with a Welfare State, are compelled to provide access to therapies, but also ...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
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Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
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Source: Journal of the American Academy of Dermatology - Category: Dermatology Authors: Source Type: research
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Source: American Journal of Health-System Pharmacy : AJHP - Category: Drugs & Pharmacology Authors: Tags: Am J Health Syst Pharm Source Type: research
Condition:   Hepatitis C Virus (HCV) Intervention:   Sponsor:   AbbVie Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: Nuclear Medicine Communications - Category: Nuclear Medicine Tags: Original Articles Source Type: research
Contributors : Sandra Franco ; Daniela Buccione ; Raquel Pluvinet ; Beatriz Mothe ; Lidia Ruiz ; Maria Nevot ; Ana Jordan-Paiz ; Laia Ramos ; Susanna Auss ó ; Rosa M Morillas ; Lauro Sumoy ; Miguel A Martinez ; Cristina TuralSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensHuman immunodeficiency virus type 1 (HIV-1)-induced inflammation and/or long-term antiretroviral drug toxicity may contribute to the evolution of liver disease. We investigated circulating plasma microRNAs (miRNAs) as potential biomarkers of liver injury in patients mono-infected with HIV-1. We performed large...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
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Source: Tropical Doctor - Category: Tropical Medicine Authors: Tags: Trop Doct Source Type: research
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Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
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