Vitrification of in vitro matured oocytes: effects on meiotic spindle configuration and mitochondrial function.
CONCLUSION: In vitro maturation (IVM) has an adverse effect on the organization of spindle and chromosome, and no significantly effect on spindle and chromosome was discovered after vitrification-thaw cycle, while there was obvious damage of oocyte mitochondrial function of in vitro-matured oocyte detected after warming, which may be the reason of the low following developmental potential.
PMID: 24696732 [PubMed - in process]
Source: International Journal of Clinical and Experimental Pathology - Category: Pathology Authors: Lei T, Guo N, Liu JQ, Tan MH, Li YF Tags: Int J Clin Exp Pathol Source Type: research