Condition can cause infertility and hair loss but what is polycystic ovary syndrome?

POLYCYSTIC Ovary Syndrome is a common condition which affects millions of women across the UK and it is one of the biggest causes of infertility in women in the UK.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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We present a case series of 11 patients with severe alopecia areata on longstanding, regular to high dose oral tofacitinib with marked hair regrowth. Additionally, we present a case of moderate to severe alopecia areata successfully treated with topical tofacitinib cream. J Drugs Dermatol. 2018;17(7):800-803. PMID: 30005104 [PubMed - in process]
Source: Journal of Drugs in Dermatology - Category: Dermatology Tags: J Drugs Dermatol Source Type: research
Publication date: Available online 28 June 2018Source: Best Practice &Research Clinical Obstetrics &GynaecologyAuthor(s): Melanie L. Walls, Roger HartAbstractIn vitro maturation (IVM) is an in vitro fertilisation (IVF) technique modified to collect immature oocytes from antral follicles, with the final stages of meiosis completed during in vitro culture. The primary benefit of IVM is that it reduces gonadotrophin stimulation in the patient, thereby eliminating the risk of ovarian hyperstimulation syndrome (OHSS) in high-risk patients such as those with polycystic ovaries (PCO) and polycystic ovary sy...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - Category: OBGYN Source Type: research
Abstract Background: In the current society, infertility related to age has become a social problem. The in vitro fertilization (IVF) success rate in women with poor ovarian response (POR) is very low. Dandelion extract T-1 (DE-T1) is an effective component of the extract from the leaves and stems of Taraxacum officinale, which is one of the medicines used in some patients with POR, but its molecular mechanism remains unclear. Methods: Following IVF, ovarian granulosa cells (GCs) of sixty patients were extracted and divided into normal ovarian response (NOR) and POR groups. GCs were cultured in a dose-depende...
Source: Chinese Medical Journal - Category: General Medicine Authors: Tags: Chin Med J (Engl) Source Type: research
ConclusionObese subjects of control and PCOS groups had higher values of TGF-β1 and lower values of plasma sEng level than lean subjects, the diagnostic power of both TGF-β1 and sEng was highly significant thus, sEng and TGF-β1 could be a useful diagnostic biomarker of PCOS.
Source: Middle East Fertility Society Journal - Category: Reproduction Medicine Source Type: research
β-arrestins and biased signalling in gonadotropin receptors. Minerva Ginecol. 2018 Jul 10;: Authors: De Pascali F, Reiter E Abstract Gonadotropin receptors include the follicle stimulating hormone receptor (FSHR) and the luteinizing hormone/choriogonadotropin receptor (LHCGR), both belong to the G protein- coupled receptor (GPCR) superfamily and being essential to reproduction. FSHR is activated by follicle stimulating hormone (FSH) while LHCGR is activated by either luteinizing hormone (LH) or choriogonadotropin (CG). Upon ligand binding, gonadotropin receptors undergo conformational changes that...
Source: Minerva Ginecologica - Category: OBGYN Tags: Minerva Ginecol Source Type: research
Authors: De Vincentis S, Monzani ML, Brigante G Abstract Gonadotropins and thyroid hormones are essential, respectively, for reproduction and metabolism. The classical endocrinological approach is based on the detection of axes that start from the hypothalamus and arrive at the final effector organ, in this case gonads and thyroid. However, several clues suggest that these axes do not work in parallel, but they dialogue with each other. In this article, we review evidences demonstrating crosstalk between gonadotropins and thyroid axis. Firstly, there is an undeniable structural similarity of both hormones and recep...
Source: Minerva Ginecologica - Category: OBGYN Tags: Minerva Ginecol Source Type: research
In this study, we aimed to examine sexual function in women with PCOS, exposed to maternal androgen excess during their prenatal life compared to non-exposed PCOS patients. In this cross-sectional study, 768 married women with PCOS, aged 18-49 years, were subdivided into two groups, based on their mothers' PCOS status: women whose mothers had PCOS (N = 94) and women whose mothers did not have PCOS (N = 674). Data were collected using a questionnaire including information on demographics, anthropometric and reproductive characteristics, and the Female Sexual Function Index. Blood serum samples were ...
Source: Archives of Sexual Behavior - Category: Psychiatry & Psychology Authors: Tags: Arch Sex Behav Source Type: research
Key content The symptoms of polycystic ovary syndrome (PCOS) include menstrual cycle disturbance and features of hyperandrogenism (hirsutism, acne and alopecia), with associated fertility problems, obesity and psychological issues. There are ethnic variations in expression of PCOS related to differences in insulin metabolism and this may impact upon treatment algorithms. Obesity has a major impact on the expression of PCOS and the efficacy of the management of all aspects of the syndrome, in particular infertility. The management of anovulatory infertility involves lifestyle modification and therapies to induce ovulati...
Source: The Obstetrician and Gynaecologist - Category: OBGYN Authors: Tags: Review Source Type: research
Authors: Laggari V, Christogiorgos S, Deligeoroglou E, Tsiantis J, Creatsas G Abstract Mayer-Rokitansky-Küster-Hauser Syndrome (MRKHS) is characterized by complete or partial absence of the vagina, uterus and proximal fallopian tubes and diagnosis is usually made in late adolescence, when primary amenorrhea appears as the major symptom. Polycystic Ovary Syndrome (PCOS), which is the most common endocrine disorder among women of reproductive age, includes a variety of clinical manifestations (menstrual irregularities, hirsuitism, acne, alopecia, obesity and infertility), due to androgen hypersecretion, insulin ...
Source: Psychiatriki - Category: Psychiatry Tags: Psychiatriki Source Type: research
Conclusion This study showed that young adult men with moderate to severe AGA have poor quality of semen compared with those who have normal to mild AGA.
Source: Dermatologica Sinica - Category: Dermatology Source Type: research
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