Neuroprotective constituent from the seeds of Alpinia katsumadai Hayata

Publication date: December 2016 Source:Phytochemistry Letters, Volume 18 Author(s): Dong-Yang Chen, Fan Yang, Yu-Qun Lin Two new compounds, named as rhamnocitrin-3-O-β-d-glucopyranosyl-4′-O-β-d-galactosyl-(1→3)-O-β-d-glucopyranoside (1), and (3R)-5,6,7-trihydroxy-3-isopropyl-3-methylisochroman-1-one (2), were isolated from the seeds of Alpinia katsumadai Hayata. Their structures were elucidated on the basis of spectroscopic analysis. Additionally, compounds 2 exhibited potent neuroprotective activity on 1-methyl-4-phenylpyridinium-induced oxidative damage in PC12 cells. Graphical abstract

Source: Phytochemistry Letters - September 6, 2016 Category: Chemistry Source Type: research