Renalase Secreted by Human Kidney HEK293T Cells Lacks its N-Terminal Peptide: Implications for Putative Mechanisms of Renalase Action

Conclusions:Lack of the N-terminal peptide, the structural precondition for FAD binding, suggests that extracellular (circulating) renalase acts in a FAD-independent manner and mechanisms of its action are not associated with FAD.Kidney Blood Press Res 2016;41:593-603
Source: Kidney and Blood Pressure Research - Category: Urology & Nephrology Source Type: research