The Importance of CD200 in Differential Diagnosis of Chronic Lymphocytic Leukemia (CLL) and Possible Role of CD200 in Existence of Infection Complications

CLL is common hematological malignancy among Armenian population. 62 patients with the suspect of lymphoid neoplasm were admitted to Hematology Center of Armenia during last 2 years. The diagnosis was based on morphological, immunophenotyping, cytogenetic and FISH methods. All CLL cases had different clinical courses which were depend on clinical stage and accompanying infection complications. 32 of these patients had infection complications mainly in form of recurrent pneumonia. As the clinical features and phenotype of CLL are very similar to Mantle cell Lymphoma (MCL), CD200 was added to standard immunophenotyping panel for differential diagnosis of CLL and MCL.
Source: Clinical Lymphoma, Myeloma and Leukemia - Category: Hematology Authors: Source Type: research