Tumor necrosis factor-alpha ( −308G/A, +488G/A, −857C/T and -1031T/C) gene polymorphisms and risk of ischemic stroke in north Indian population: A hospital based case–control study

Conclusions Two SNPs (+488G/A and -857C/T) of TNF-α gene and their haplotypes are significantly associated with the risk of IS in the population enrolled from North India. Our findings indicate that polymorphisms and haplotypes of TNF-α gene may be used as a genetic marker for identifying individuals at increased risk for developing IS.
Source: Meta Gene - Category: Genetics & Stem Cells Source Type: research