The importance of non-HLA antibodies in transplantation

Nature Reviews Nephrology 12, 484 (2016). doi:10.1038/nrneph.2016.88 Authors: Qiuheng Zhang & Elaine F. Reed The development of post-transplantation antibodies against non-HLA autoantigens is associated with rejection and decreased long-term graft survival. Although our knowledge of non-HLA antibodies is incomplete, compelling experimental and clinical findings demonstrate that antibodies directed against autoantigens such as angiotensin type 1 receptor, perlecan and collagen,
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Review Source Type: research