Inhibiting cortical protein kinase a in spinal cord injured rats enhances efficacy of rehabilitative training.

In conclusion, blocking PKA in cortical neurons of spinal cord injured rats increases neurite outgrowth of the lesioned corticospinal tract fibres and the efficacy of rehabilitative training, likely via EPAC. PMID: 27401133 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/27401133?dopt=Abstract

Source: Experimental Neurology - July 7, 2016 Category: Neurology Authors: Wei D, Hurd C, Galleguillos D, Singh J, Fenrich KK, Webber CA, Sipione S, Fouad K Tags: Exp Neurol Source Type: research